| Smith K, Hopp M, Mundin G et al. |
Clin. Ther. 2008, 30(11), 2051-2068 |
Single- and Multiple-Dose Pharmacokinetic Evaluation of Oxycodone and Naloxone in an Opioid Agonist/Antagonist Prolonged-Release Combination in Healthy Adult Volunteers |
| Simpson K, Leyendecker P, Hopp M et al. |
Curr. Med. Res. Opin. 2008, 24(12), 3503-3512 |
Fixed-ratio combination oxycodone/naloxone compared with oxycodone alone for the relief of opioid-induced constipation in moderate to-severe noncancer pain |
| Mikus G |
Eur. Gastroenterol Hepatol Rev 2009, 4(2), 71-74 |
Combining opioid agonists and antagonists as a solution for opioid-induced constipation |
| Meissner W, Leyendecker P, Mueller-Lissner S et al. |
Eur. J. Pain 2009, 13, 56-64 |
A randomised controlled trial with prolonged-release oral oxycodone and naloxone to prevent and reverse opioid-induced consitpation |
| Löwenstein O, Leyendecker P, Hopp M et al. |
Expert Opin Pharmacother 2009, 10(4), 531-543 |
Combined prolonged-release oxycodone and naloxone improves bowel function in patients receiving opioids for moderate-to-severe non-malignant chronic pain: a randomised controlled trial |
| Nadstawek J, Leyendecker P, Hopp M et al. |
Int. J. Clin. Pract. 2008, 62, 1159-1167 |
Patient assessment of a novel therapeutic approach for the treatment of severe, chronic pain |
| Vondrackowa D, Leyendecker P, Meissner W et al. |
J. Pain 2008, 9(12), 1144-1154 |
Analgesic Efficacy and Safety of Oxycodone in Combination with Naloxone as Prolonged Release Tablets in Patients with Moderate to Severe Chronic Pain |
| Reimer K, Hopp M, Zenz M et al. |
Pharmacology 2009, 83, 10-17 |
Meeting the Challenges of Opioid-Induced Constipation in Chronic Pain Management – A Novel Approach |
